Results for collagen stimulators are gradual. You will not see instant results when using a collagen stimulator, however after repeated treatments, we suggest 3-4 treatments of one vial spaced 6 weeks apart, you will notice a fuller appearance of the treatment. Results will last up to 2.5years. Once patients have had their initial dose, the only require a top up of one vial once a year. Collagen stimultors work very well in combination with modalities of anti aging provided within the clinic.